140687-75-8

Upstream product

• 6814-64-8 methylenedimethyl sulfurane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 75-18-3 dimethylsulfide 
• 77-78-1 dimethyl sulfate 
• 6380-23-0 3,4-dimethoxystyrene 
• 23616-79-7 benzyltri(n-butyl)ammonium chloride 
• 2181-44-4 trimethylsulfonium methylsulfate 
• 4497-40-9 3,4-dimethoxy-cinnamaldehyde 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 2181-42-2 trimethylsulphonium iodide 
• 24702-26-9 S-p-Tolyl-S-methyl-N-p-tosylsulfimid 
• 958009-31-9 N-[1-(3,4-Dimethoxy-phenyl)-eth-(Z)-ylidene]-4-methyl-benzenesulfonamide 

Downstream Products

• 147624-53-1 1-(3,4-dimethoxyphenyl)-2-(benzyloxy)ethanol 
• 80101-59-3 1-(3,4-Dimethoxy-phenyl)-2-piperazin-1-yl-ethanol 
• 140687-83-8 2-(3',4'-Dimethoxyphenyl)-2-[(2,2-dimethoxyethyl)amino]ethanol 
• 843651-84-3 2-(N-tert-butyloxycarbonylaminooxy)-1-(3',4'-dimethoxyphenyl) ethanol 
• 5703-21-9 3,4-dimethoxyphenylacetaldehyde 
• 102104-67-6 3-<6-<2-hydroxy-2-(3,4-dimethoxyphenyl)ethylamino>hexyl>-1,3-thiazolidine 
• 1393913-66-0 1-(3,4-dimethoxy-phenyl)-2-(2,8-dimethyl-1,2,3,4-tetrahydro-pyrido[4,3-b]indol-5-yl)-ethanol 
• 913626-91-2 (2S,4R,9aR)-4-(3,4-dimethoxyphenyl)octahydro-1H-quinolizin-2-ol 

Relevant academic research and scientific papers

Rh-IndOlefOx catalyzed conjugate addition/Heck-type coupling of organoboronics to a lactam or a lactone

Four indole-olefin-oxazoline (IndOlefOx) ligands were synthesized and evaluated in Rh-catalyzed reactions between organoboronics and a lactam or a lactone. In addition to the expected conjugate addition products, the formation of significant amounts of Heck-type products was observed. The scope and limitations of these reactions were investigated.

Synthesis of some electron-rich aryl(hetaryl)oxiranes under phase-transfer and homogeneous conditions

Reactions of mono-, di-, and trimethoxybenzaldehydes with trimethylsulfonium methyl sulfate readily occur under mild homogeneous and heterogeneous phase-transfer conditions to give the corresponding aryloxiranes whose yields are comparable with those typi

Alkene epoxidation with urea-hydrogen peroxide complex and PS-DVB supported phthalic anhydride

A new PS-DVB supported phthalic anhydride and UHP (urea-hydrogen peroxide complex) have been used for metal-free alkene epoxidation reactions. The resin was prepared by MW mediated 'PEGylation' of Merrifield resin followed by esterification with trimellitic anhydride chloride. Epoxidation of several alkenes was carried out with this resin and UHP.

INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES

Compositions and methods of using compositions for treatment of inflammatory diseases and immune disorders are provided. Allylhydrazine compounds, hydroxylamine (aminooxy) compounds, and other compounds are disclosed which are inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein 1 (VAP-1). The compounds have therapeutic utility in suppressing inflammation and inflammatory responses, and in treatment of several disorders, including multiple sclerosis.

Enantioselective synthesis of epoxides and aziridines by asymmetric methylidene transfer from a sulfimide to carbonyl compounds and imines

The sodium salt of sulfimide 2 is a useful asymmetric methylidene transfer agent for the synthesis of enantiomerically enriched epoxides and aziridines. Moderate enantioselectivities are observed with a broad range of carbonyl compounds and with imines. An enantiomerically enriched β-adrenoreceptor agonist analogue was prepared using the new method.

Development of a polymer bound Wittig reaction and use in multi-step organic synthesis for the overall conversion of alcohols to β-hydroxyamines

An efficient combinatorial access to β-hydroxyamines suitable for automation is achieved by the mild oxidation of alcohols to aldehydes by polymer supported perruthenate (PSP), the subsequent clean olefination of the obtained aldehydes by polymer supported Wittig reagents followed by the epoxidation of the olefins by dimethyldioxirane (DMDO), and the final aminolysis of the epoxides with various amines is described.

Extension of the Bobbitt acetal cyclization to the elaboration of 1-hydroxymethyl-substituted simple tetrahydroisoquinolines. A new synthesis of calycotomine

Aromatic benzyloxymethyl ketones are convenient intermediates for the elaboration, via the Bobbitt acetal cyclization, of 1-hydroxymethyl-substituted simple tetrahydroisoquinolines, such as calycotomine and one bearing the 1,7,8-oxygenated substitution pa

Process for the preparation of 1-alkylisoquinoline derivatives

The invention relates to a process for the preparation of 1-alkyl-1,2,3,4-tetrahydroisoquinoline derivatives of the general formula STR1 The compounds can be used for the preparation of tetrahydroisoquinolines of the reticuline type, or of the norreticuli

A Convenient Strategy for Homologation of p-Oxygenated Benzaldehydes

It is shown that p-oxygenated benzaldehydes can be conveniently obtained by pyrolysis of the corresponding oxiranes.