140710-98-1

Basic information

• Product Name: (6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol
• Synonyms: (6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol;Bis-TBDMS-trans-calcitriol;1,3-bi-TBS-trans-Calcitriol
• CAS NO: 140710-98-1
• Molecular Formula: C₃₉H₇₂O₃Si₂
• Molecular Weight: 647.17406
• Mol File: 140710-98-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 621.9±55.0 °C(Predicted)
• Appearance: /
• Density: 0.95±0.1 g/cm3(Predicted)
• PKA: 15.32±0.29(Predicted)
• CAS DataBase Reference: (6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol(140710-98-1)
• EPA Substance Registry System: (6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol(140710-98-1)

Safety Data

• Hazardous Substances Data: 140710-98-1(Hazardous Substances Data)

Usage

General Description

The chemical "(6R)-6-((1R,3aS,7aR)-4-((E)-2-((3S,5R)-3,5-bis(tert-butyldiMethylsilyloxy)-2-Methylenecyclohexylidene)ethyl)-7a-Methyloctahydro-1H-inden-1-yl)-2-Methylheptan-2-ol" is a complex compound with a long molecular structure. It contains a mixture of various functional groups including alcohol, alkene, and cycloalkane moieties. The compound likely has biological and pharmacological activities due to its stereochemical arrangement and functional groups. Its structural complexity suggests that it may have potential applications in the fields of organic chemistry, pharmaceuticals, and medicinal research. However, further studies and investigation are needed to fully understand the properties and potential uses of this compound.

Upstream product

• 184851-16-9 C₄₀H₇₂O₂Si₂ 
• 917-64-6 methyl magnesium iodide 
• 147125-06-2 (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-20(S)-(iodomethyl)-9,10-secopregna-5(E),7(E),10(19)-triene 
• 128387-35-9 (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-20(S)-(hydroxymethyl)-9,10-secopregna-5(E),7(E),10(19)-triene 
• 170081-46-6 (6S)- and (6R)-SO₂ adducts of 1(S),3(R)-bis(tert-butyldimethylsilyloxy)-9,10-secoergosta-5(E),7(E),10⁽¹⁹⁾,22(E)-tetraene 
• 75-16-1 methylmagnesium bromide 
• 169900-32-7 ethyl (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-seco-26,27-bisnorcholesta-5(E),7(E),10(19)-trien-25-oate 

Downstream Products

• 140710-96-9 (1S),3(R)-bis<(tert-butyldimethylsilyl)oxy>-9,10-secocholesta-5(Z),7(E),10(19)-trien-25-ol 
• 73837-24-8 (1S),3(R)-9,10-secocholesta-5(E),7(E),10⁽¹⁹⁾-triene-1,3,25-triol 
• 32222-06-3 calcitriol 

Relevant articles and documents

Preparation method of 25-hydroxyvitamin D3, 1alpha, 25-dihydroxyvitamin D3 and isotope internal standard compound thereof

The invention discloses a preparation method of 25-hydroxyvitamin D3 and 1alpha, 25-dihydroxyvitamin D3 and an isotope internal standard compound thereof. The preparation method comprises the following steps: a compound III is subjected to SO2 conjugate protection, O3 oxidation, NaBH4 reduction, iodination ring opening, conjugate addition with acrylate, and reaction with a methyl Grignard reagentor isotope labeled methyl Grignard reagent, a silicon protecting group is removed under the action of TBAF, and a product is obtained through ultraviolet irradiation configuration inversion under thecatalysis of 9-acetyl anthracene. The method is good in reaction selectivity, high in total yield, simple and convenient to operate and short in isotope introduction step, and the isotope utilizationrate is greatly increased.