1407186-36-0Relevant academic research and scientific papers
N-Heterocyclic carbene triazolium salts containing brominated aromatic motifs: Features and synthetic protocol
Raed, Anas Abo,Dhayalan, Vasudevan,Barkai, Shahar,Milo, Anat
, p. 878 - 882 (2020/12/25)
In this work, we provide a brief overview of the role of N-aryl substituents on triazolium N-heterocyclic carbene (NHC) catalysis. This synopsis provides context for the disclosed synthetic protocol for new chiral N-heterocyclic carbene (NHC) triazolium salts with brominated aromatic motifs. Incorporating brominated aryl rings into NHC structures is challenging, probably due to the substantial steric and electronic influence these substituents exert throughout the synthetic protocol. However, these exact characteristics make it an interesting N-aryl substituent, because the electronic and steric diversity it offers could find broad use in organometallic- A nd organo-catalysis. Following the synthetic reaction by NMR guided the extensive modification of a known protocol to enable the preparation of these challenging NHC pre-catalysts.
