1407186-37-1

Upstream product

• 420-37-1 trimethoxonium tetrafluoroborate 
• 249617-43-4 (+)-(S)-5-(Diphenylmethyl)pyrrolidin-2-one 
• 98-79-3 L-Pyroglutamic acid 
• 4931-66-2 methyl (S)-pyroglutamate 

Downstream Products

• 1356583-11-3 (S)-5-benzhydryl-2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium chloride 
• 1447813-77-5 (S)-5-benzhydryl-2-(2,6-dimethoxyphenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium chloride 
• 1447813-81-1 (S)-5-benzhydryl-2-(2,6-diethylphenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium chloride 
• 1447823-10-0 (S,Z)-2-benzhydryl-5-(2-mesitylhydrazono)pyrrolidine hydrochloride 
• 1447823-11-1 (S,Z)-2-benzhydryl-5-(2-(2,6-dimethoxyphenyl)hydrazono)pyrrolidine hydrochloride 
• 1447823-12-2 (S,Z)-2-benzhydryl-5-(2-(2,6-diethylphenyl)hydrazono)pyrrolidine hydrochloride 
• 1447823-14-4 (S,Z)-2-benzhydryl-5-(2-(2,6-diisopropoxyphenyl)hydrazono)pyrrolidine hydrochloride 
• 1447813-87-7 (S)-5-benzhydryl-2-(2,6-diisopropoxyphenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium chloride 

Relevant academic research and scientific papers

Enantioselective N-Heterocyclic Carbene Catalysis by the Umpolung of α,β-Unsaturated Ketones

N-Heterocyclic carbene-catalyzed formation of β-anionic intermediates from enones has been employed in the enantioselective synthesis of 2-aryl propionates. The reaction was achievable using a homochiral 4-MeOC6H4 morpholinone cataly

Highly enantioselective intermolecular stetter reaction of simple acrylates: Synthesis of α-chiral γ-Ketoesters

Simple Stetter: A novel N-heterocyclic carbene (NHC) was designed by combining an electron-rich 2,6-dimethoxy substituent and an underestimated yet promising chiral motif. With this NHC in hand, a highly enantioselective intermolecular Stetter reaction of simple acrylates was developed, yielding versatile α-chiral γ-ketoesters. This represents the first catalytic asymmetric route towards these valuable compounds (see scheme).