1407489-40-0

Basic information

• Product Name: methyl 4-((9H-fluoren-9-ylidene)methyl)benzoate
• Synonyms: methyl 4-((9H-fluoren-9-ylidene)methyl)benzoate
• CAS NO: 1407489-40-0
• Molecular Weight: 312.368
• Mol File: 1407489-40-0.mol

Chemical Properties

• CAS DataBase Reference: methyl 4-((9H-fluoren-9-ylidene)methyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-((9H-fluoren-9-ylidene)methyl)benzoate(1407489-40-0)
• EPA Substance Registry System: methyl 4-((9H-fluoren-9-ylidene)methyl)benzoate(1407489-40-0)

Safety Data

• Hazardous Substances Data: 1407489-40-0(Hazardous Substances Data)

Upstream product

• 2113-51-1 2-iodobiphenyl 
• 13379-29-8 2-bromo-2'-(bromomethyl)-1,1'-biphenyl 
• 125587-45-3 methyl 4-[(2-tosylhydrazono)methyl]benzoate 
• 253684-21-8 1,1-dibromo-2-(4-methoxycarbonylphenyl)ethene 
• 5565-85-5 5,5-dimethyl-5H-dibenzo[b,d]stannole 
• 251320-87-3 2-bromo-2'-methylbiphenyl 

Relevant articles and documents

Palladium-catalyzed coupling reaction of 2-iodobiphenyls with alkenyl bromides for the construction of 9-(diorganomethylidene)fluorenes

An atom economical protocol for the construction of 9-(diorganomethylidene)fluorenes through palladium-catalyzed coupling reactions of 2-iodobiphenyls with alkenyl bromides has been reported. The reaction proceeds through the C-H activation/oxidative addition/reduction elimination/intramolecular Heck coupling reaction to afford a series of 9-(diorganomethylidene)fluorenes with good yields. Control experiments demonstrate that a five-membered palladacycle acts as a key intermediate and β-H elimination serves as the rate-limiting step.

Pd-Catalyzed Autotandem Reactions with N-Tosylhydrazones. Synthesis of Condensed Carbo- and Heterocycles by Formation of a C-C Single Bond and a C-C Double Bond on the Same Carbon Atom

A new Pd-catalyzed autotandem reaction is introduced that consists of the cross-coupling of a benzyl bromide with a N-tosylhydrazone followed by an intramolecular Heck reaction with an aryl bromide. During the process, a single and a double C-C bond are formed on the same carbon atom. Two different arrangements for the reactive functional groups are possible, rendering great flexibility to the transformation. The same strategy led to 9-methylene-9H-fluorenes, 9-methylene-9H-xanthenes, 9-methylene-9,10-dihydroacridines, and also dihydropyrroloisoquinoline and dihydroindoloisoquinoline derivatives.

New synthesis of dibenzofulvenes by palladium-catalyzed double cross-coupling reactions

Palladium-catalyzed double cross-coupling reactions of 1,1-bis(pinacolato) borylalk-1-enes with 2,2′-dibromobiaryls and of 9-stannafluorenes with 1,1-dibromoalk-1-enes have been demonstrated to serve as new synthetic methods for dibenzofulvenes.