253684-21-8

Basic information

• Product Name: methyl 4-(2,2-dibromovinyl)benzoate
• Synonyms: methyl 4-(2,2-dibromovinyl)benzoate
• CAS NO: 253684-21-8
• Molecular Formula: C₁₀H₈Br₂O₂
• Molecular Weight: 320
• Mol File: 253684-21-8.mol
• Article Data: 22

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: methyl 4-(2,2-dibromovinyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2,2-dibromovinyl)benzoate(253684-21-8)
• EPA Substance Registry System: methyl 4-(2,2-dibromovinyl)benzoate(253684-21-8)

Safety Data

• Hazardous Substances Data: 253684-21-8(Hazardous Substances Data)

Upstream product

• 1571-08-0 methyl 4-formylbenzoate 
• 558-13-4 carbon tetrabromide 

Downstream Products

• 1074-61-9 (4-vinyl-phenyl)-methanol 
• 117417-08-0 (E)-1-bromo-2-(4-hydroxymethylphenyl)ethene 
• 1232144-42-1 C₁₆H₁₂ClNO₃ 
• 1232144-38-5 C₁₆H₁₃NO₃ 
• 936138-80-6 C₁₆H₁₂N₂O₅ 
• 115665-79-7 (E)-4-(β-bromovinyl)benzoic acid methyl ester 
• 356759-39-2 (Z)-4-(β-bromovinyl)benzoic acid methyl ester 
• 79370-16-4 trans-4-Methoxy-4'-stilbencarbonsaeure-methylester 
• 1096357-12-8 C₂₂H₁₈N₂O₂ 
• 1096357-09-3 C₁₇H₁₆N₂O₂ 
• 225928-10-9 4-(bromoethynyl)benzoic acid methyl ester 
• 1096357-10-6 C₁₆H₁₃BrN₂O₂ 

Relevant articles and documents

Nickel-Catalyzed, Regio- and Enantioselective Benzylic Alkenylation of Olefins with Alkenyl Bromide

A NiH-catalyzed migratory hydroalkenylation reaction of olefins with alkenyl bromides has been developed, affording benzylic alkenylation products with high yields and excellent chemoselectivity. The mild conditions of the reaction preclude olefinic products from undergoing further isomerization or subsequent alkenylation. Catalytic enantioselective hydroalkenylation of styrenes was achieved by using a chiral bisoxazoline ligand.

A Radical-Initiated Fragmentary Rearrangement Cascade of Ene-Ynamides to [1,2]-Annulated Indoles via Site-Selective Cyclization

Straightforward access to [1,2]-annulated indoles, key substructures in natural products, is highly desirable yet challenging. Herein, a radical triggered fragmentary cyclization cascade reaction of ene-ynamides is presented, providing a rapid access into [1,2]-annulated indoles by an intermolecular radical addition, intramolecular cyclization, desulfonylative aryl migration, and site-selective C(sp2)-N cyclization sequence. DFT calculations support oxidation of N-centered radical species to cations prior to the C-N bond formation, followed by an unusual aza-Nazarov cyclization.

N -tert-butyl -2 -phenylindole derivative Preparation method and application

The invention belongs to the technical field of organic synthesis, and particularly relates to N - tert-butyl -2 -phenyl indole derivatives as well as a preparation method and application thereof. The preparation method comprises the following steps: (Z)-1 - bromo -1 - phenyl -2 - styrene derivative, N, N - di-tert-butyl diazepinone, palladium catalyst, monophosphine ligand, hydrocarbon activator, base and first solvent, and N -tert-butyl -2 -aryl indole derivatives which can synthesize substituent type diversity, and the prepared N -tert-butyl -2 -aryl indole derivative can be used for preparing biologically active molecules N -2 .