1407666-67-4

Upstream product

• 1102373-43-2 C₉H₆ClF₃O 
• 1407666-56-1 (S)-4-benzyl-3-(3-(2,4,5-trifluorophenyl)propanoyl)oxazolidin-2-one 
• 1407666-61-8 (R)-t-butyl 4-((S)-4-benzyl-2-oxo-oxazolidin-3-yl)-4-oxo-3-(2,4,5-trifluorobenzyl)butanoate 
• 651047-33-5 3-(2,4,5-trifluorophenyl)propanoic acid 

Downstream Products

• 1407666-72-1 (R)-tert-butyl 3-(((benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoate 
• 486460-32-6 sitagliptin 
• 1242069-63-1 (R)-benzyl (4-oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl)carbamate 
• 1246960-25-7 (R)-3-(((benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid 
• 1407666-69-6 C₁₅H₁₆F₃NO₃ 

Relevant academic research and scientific papers

PROCESS FOR THE PRODUCTION OF SITAGLIPTIN

A novel process is described for the synthesis of Sitagliptin, IUPAC name 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine, of formula (I).

PROCESS FOR THE PRODUCTION OF SITAGLIPTIN

A novel process is described for the synthesis of Sitagliptin, lUPAC name 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1 2,4-triazolo[4,3-a]pyrazine, of formula (I).