1407870-28-3Relevant articles and documents
Ligand-enabled methylene C(sp3)-H bond activation with a Pd(II) catalyst
Wasa, Masayuki,Chan, Kelvin S. L.,Zhang, Xing-Guo,He, Jian,Miura, Masanori,Yu, Jin-Quan
, p. 18570 - 18572 (2013/01/15)
Pd(II) insertion into β-methylene C(sp3)-H bonds was enabled by a mutually repulsive and electron-rich quinoline ligand. Ligand tuning led to the development of a method that allows for installation of an aryl group on a range of acyclic and cyclic amides containing β-methylene C(sp3)-H bonds.