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1407991-27-8

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1407991-27-8 Usage

General Description

(3R)-piperidine-3-carbonitrile hydrochloride is a chemical compound with the molecular formula C6H10N2.HCl. It is a derivative of piperidine, which is a six-membered nitrogenous heterocycle. (3R)-piperidine-3-carbonitrile hydrochloride is a white solid that is soluble in water and other polar solvents. It is primarily used in organic synthesis and medicinal chemistry as a building block for the preparation of a variety of pharmaceuticals and other organic compounds. The hydrochloride salt form of (3R)-piperidine-3-carbonitrile is commonly used for its stability and improved solubility compared to the free base form. It is an important intermediate in the production of pharmaceutical drugs and occasionally used in research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1407991-27-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,7,9,9 and 1 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1407991-27:
(9*1)+(8*4)+(7*0)+(6*7)+(5*9)+(4*9)+(3*1)+(2*2)+(1*7)=178
178 % 10 = 8
So 1407991-27-8 is a valid CAS Registry Number.

1407991-27-8Relevant articles and documents

Carbazole inhibitors of histamine receptors for the treatment of disease

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Page/Page column 38, (2012/01/04)

The present invention relates to carbazole compounds, pharmaceutical compositions comprising them, and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

PHENYL-3-{ (3- (1H- PYRROL- 2 -YL) - [1 , 2 , 4] 0XADIAZ0L-5-YL] PIPERIDIN-1-YL}-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

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, (2008/06/13)

The present invention provides new compounds of formula (I) as positive allosteric modulators of metabotropic receptors - subtype 5 ("mGluR5") which are useful for the treatment or prevention of central nervous system disorders such as for example, cognitive decline, both positive and negative symptoms in schizophrenia as well as other central or peripheral nervous system disorders in which the mGluR5 subtype of glutamate metabotropic receptor is involved. The invention is also directed to pharmaceutical compounds and compositions in the prevention or treatment of such diseases in which mGluKi is involved. W represents (C4-C7)cycloalkyl, (C3-C7)heterocycloalkyl , (C3-C7)heterocycloalkyl-(C1-C3)alkyl or (C3-C7)heterocycloalkenyl ring; represents a (C5-C7)heteroeycloalkyl, (C5-C7)heterocycloalkeiiyl ring or a heteroaryl group of formula (a), (b), (c), (d), (e), (f), (g), (i). Q denotes a cycloalkyl, an aryl or heteroaryl group of formula (j), (k), (l), (m), (n). A is azo -N=N-, ethyl, ethenyl, ethynyl, -NR8C(=O)-, -NR8C(=O)-O-, -NR8C(=O)-NR9, NR8S(=O)2-, -C(=O)NR8-, -O-C(=O)NR8-, -S-, -S(=O)-, -S(=O)2-, -S(C=O)2NR8-, -C(=0)-0-, -0-C(=0)-, -C(=NR8)NR9-, C(C=NOR8)NR9- , -NR8C(=NOR9)-, =N-0-, -0-N=CH- or a group aryl or heteroaryl of formula, (o), (p), (q), (r), (s), (t), (u), (v), (w), (x). The other substituents are defined in the claims.

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