1408282-63-2Relevant academic research and scientific papers
New matrix metalloproteinase inhibitors based on γ-fluorinated α-aminocarboxylic and α-aminohydroxamic acids
Behrends, Malte,Wagner, Stefan,Kopka, Klaus,Schober, Otmar,Sch?fers, Michael,Kumbhar, Sadhana,Waller, Mark,Haufe, Günter
, p. 3809 - 3818 (2015/08/03)
Abstract Matrix metalloproteinases (MMPs) are involved in a number of physiological as well as pathological processes such as atherosclerosis and tumorigenesis, where an up-regulation of MMPs is predominant. Fluorinated analogues of the hydroxamate-based
Compounds with Matrix-Metalloproteinase Inhibitory Activity and Imaging Agents Thereof
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, (2012/11/13)
The present invention relates to the field of therapeutic and diagnostic agents and more specifically to compounds of formula (I) that are inhibitors of matrix-metalloproteinases (MMPs) and are useful in the treatment of diseases related thereto such as c
