140833-97-2Relevant academic research and scientific papers
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity
Antonaroli,Bianco,Brufani,Cellai,Lo Baido,Potier,Bonomi,Perfetti,Fiaschi,Segre
, p. 2697 - 2703 (2007/10/02)
New carbonic anhydrase (EC 4.2.1.1) inhibitors were synthesized as potential drugs for the topical treatment of glaucoma. They were obtained by substituting the acetyl group of acetazolamide and methazolamide with bicarboxylic acids of different chain len
Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same
-
, (2008/06/13)
Compounds related to acetazolamide and to its N-methyl derivatives, of the formulae: STR1 wherein Y is one of the following groups: STR2 R1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
Acetazolamide-related compounds, process for their preparation, and pharmaceutical composition containing the same
-
, (2008/06/13)
Compounds related to acetazolamide and to its N--methyl derivatives, of the formulae: wherein Y is one of the following groups: R1 being a straight or branched alkylene or arylalkylene, or a phenylene, and the processes for their preparation; the compounds so obtained are inhibitors of carbonic anhydrase like acetazolamide but, in addition, they are well absorbed topically so that they can be used as drugs for treating glaucoma.
