140835-51-4Relevant academic research and scientific papers
Acylnitrilium ion initiated heteroannulations in alkaloid synthesis. An efficient, stereocontrolled, total synthesis of the Orchidaceae alkaloid (±)-dendrobine
Lee, Cheol Hae,Westling, Mark,Livinghouse, Tom,Williams, Andrew C.
, p. 4089 - 4095 (1992)
A concise total synthesis of (±)-dendrobine is described that proceeds in eight steps from 2-methylcyclopent-2-en-1-one. The key transformation in this approach is the silver ion mediated cyclocondensation of the isonitrile 6 with the acyl chloride 5. Thi
