140846-08-8Relevant academic research and scientific papers
Efficient synthesis of novel imidazo[1,2-a]pyrimidine derivatives via one-pot three-component procedure
Sadjadi, Samahe,Nahavandi, Fatemeh,Heravi, Majid
, p. 1049 - 1052 (2015)
Abstract Synthesis of novel derivatives of imidazo[1,2-a]pyrimidine from one-pot three-component reaction of aldehydes, 2-amino-benzimidazole, and α-tetralone in the presence of catalytic amount of p-toluene sulfonic acid under reflux condition in EtOH has been presented. The simplicity and safety of the process, high yields and short reaction times were the main advantages of this protocol.
IMINE-ENAMINE TAUTOMERISM IN DIHYDROAZOLOPYRIMIDINES. 2. SYNTHESIS AND TAUTOMERISM OF 1,4(3,4)-DIHYDROPYRIMIDOBENZIMIDAZOLES
Desenko, S. M.,Orlov, V. D.,Lipson, V. V.,Estrada, Kh.
, p. 976 - 980 (2007/10/02)
Cyclocondensation of 2-aminobenzimidazole with unsaturated ketones or the hydrochlorides of Mannich bases has yielded aromatic substituted 1,4(3,4)-dihydropyrimidobenzimidazoles.The dependence of the tautomer composition of the products on steric factors and on the electronic character of the substituents introduced has been studied.
