140860-59-9

Upstream product

• 128791-84-4 (4S,5R)-5-Benzo[1,3]dioxol-5-yl-4-(tert-butyl-dimethyl-silanyloxymethyl)-3-trimethylsilanyl-dihydro-furan-2-one 
• 100-52-7 benzaldehyde 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 16108-37-5 trans-4-hydroxymethyl-5-(3,4-methylenedioxyphenyl)-dihydrofuran-2(3H)-one 
• 128791-83-3 (+/-)-trans-4-(tert-butyldimethylsilyloxymethyl)-5-(3,4-methylenedioxyphenyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

Stereospecific Synthesis of the 2,3-trans-3,4-cis Trisubstituted Tetrahydrofuran Lignan(+/-)-Dihydrosesamin

It is shown that the stereochemistry of additions to the 3-arylidene lactones 3 and 9 is controlled by the 5- rather than the 4-substituent; synthesis of the 2,3-trans-3,4-cis lignan dihydrosesamin 11b (R = H) thus requires use of the 4,5-cis- lactone 8,