14094-12-3Relevant articles and documents
McLennan
, p. 709,712 (1966)
Large-steric-hindrance alkyl-alkyl sulfone compound as well as synthesis method and application thereof
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Paragraph 0173-0176, (2020/07/24)
The invention belongs to the technical field of organic compound synthesis and application, and discloses a large-steric-hindrance alkyl-alkyl sulfone compound shown as a formula (4) and a synthesis method thereof. Carboxylic acid derived redox ester, a reducing sulfur dioxide source and an alkyl electrophilic reagent are used as raw materials, and a series of large-steric-hindrance alkyl-alkyl sulfone compounds are obtained by a three-component one-pot method. The synthesis method is wide in raw material source, cheap and easy to obtain; the reaction operation is simple; the functional grouptolerance is high; the use of a reducing sulfur dioxide source in the reaction avoids the addition of an additional equivalent metal reducing reagent, is economical and practical, and avoids the pollution of waste metals to the environment. The invention also discloses application of the alkyl-alkyl sulfone compound in preparation of drugs, pesticides, organic photoelectric materials and the like.The method has high practical value and wide application prospect.
Efficient and selective hydrogen peroxide-mediated oxidation of sulfides in batch and segmented and continuous flow using a peroxometalate-based polymer immobilised ionic liquid phase catalyst
Doherty,Knight,Carroll,Ellison,Hobson,Stevens,Hardacre,Goodrich
supporting information, p. 1559 - 1571 (2015/03/18)
The peroxometalate-based polymer immobilized ionic liquid phase catalyst [PO4{WO(O2)2}4]@PIILP has been prepared by anion exchange of ring opening metathesis-derived pyrrolidinium-decorated norbornene/cyclooctene copolymer and shown to be a remarkably efficient system for the selective oxidation of sulfides under mild conditions. A cartridge packed with a mixture of [PO4{WO(O2)2}4]@PIILP and silica operated as a segmented or continuous flow process and gave good conversions and high selectivity for either sulfoxide (92% in methanol at 96% conversion for a residence time of 4 min) or sulfone (96% in acetonitrile at 96% conversion for a residence time of 15 min). The immobilized catalyst remained active for 8 h under continuous flow operation with a stable activity/selectivity profile that allowed 6.5 g of reactant to be processed (TON = 46 428) while a single catalyst cartridge could be used for the consecutive oxidation of multiple substrates giving activity-selectivity profiles that matched those obtained with fresh catalyst.
