14097-41-7

Upstream product

• 69062-43-7 2-methyl-5-nitro-1,2,3,4-tetrahydro-isoquinoline 
• 19384-71-5 5-amino-2-methylisoquinolinium iodide 
• 54410-11-6 2-methyl-5-nitro isoquinolinium methyl sulphate 
• 1125-60-6 isoquinolin-5-ylamine 
• 1612-65-3 2-methyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 56135-34-3 5-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline 
• 37481-36-0 5-(2-Chlorobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-37-1 5-(2-Fluorobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-39-3 5-(2,6-dimethoxybenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-42-8 5-(2,6-diethylbenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-45-1 5-(2-bromobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 27461-31-0 3,4,5-trimethoxy-N-(2-methyl-1,2,3,4-tetrahydro-isoquinolin-5-yl)-benzamide 
• 37481-44-0 5-(2-iodobenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 
• 37481-41-7 5-(2,6-dimethylbenzamido)-2-methyl-1,2,3,4-tetrahydroisoquinoline 

Relevant academic research and scientific papers

THERAPEUTIC METHODS AND COMPOUNDS

The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.

Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides

SAR studies around a series of N-(tetrahydroisoquinolinyl)-2-methoxybenzamides, identified by high-throughput screening at the novel SB-204269 binding site, have provided compounds such as 13, 29-33 with high affinity and excellent anticonvulsant activity in animal models. Copyright (C) 2000 Elsevier Science Ltd.

Identification of a series of 1,2,3,4-tethydroisoquinolinylbenzamides with potential anticonvulsant activity

A series of N-(tetrahydroisoquinolinyl)-2-methoxybenzamides was identified by high-throughput screening at the novel SB-204269 binding site. SAR studies have provided compounds 4 and 14 with high affinity and good anticonvulsant activity in animal models.

Isatineoxime derivatives, their preparation and use

A compound having the formula STR1 wherein R4 and R5 independently are hydrogen, halogen, CF3, CN, NO2 or SO2 NR1 R2 wherein R1 is hydrogen or C1-6 -alkyl w

Isatinoxime derivatives, their preparation and use

A compound having the formula STR1 wherein R 4 and R 5 independently are hydrogen, halogen, CF 3, CN, NO 2 or SO 2 NR 1 R 2 whereinR 1 is hydrogen or straight, C 1-6 -alkyl which may be branched or cyclic,R 2 is hydrogen or straight, C 1-6 -alkyl which ma