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2,6-Dimethyl-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide, also known as SB 265610, is a chemical compound belonging to the benzamides class. It is a potent and selective antagonist for the 5-HT6 serotonin receptor, a G protein-coupled receptor predominantly located in the central nervous system. This receptor is involved in various physiological and pathological processes, such as cognition, mood regulation, and neurodegenerative diseases. SB 265610 has been investigated for its potential therapeutic effects in treating neurodegenerative disorders like Alzheimer's disease and schizophrenia, due to its ability to modulate serotonin neurotransmission in the brain. Additionally, it serves as a valuable research tool in neuroscience and drug development.

37481-41-7

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37481-41-7 Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dimethyl-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide is used as a therapeutic agent for neurodegenerative disorders such as Alzheimer's disease and schizophrenia. Its application is based on its ability to modulate serotonin neurotransmission in the brain, potentially improving cognitive function and alleviating symptoms associated with these conditions.
Used in Research and Drug Development:
2,6-Dimethyl-N-(1,2,3,4-tetrahydro-2-methylisoquinolin-5-yl)benzamide is used as a research tool in the field of neuroscience and drug development. Its selectivity as a 5-HT6 serotonin receptor antagonist makes it valuable for studying the receptor's role in cognitive and mood-related processes, as well as for developing new therapeutic agents targeting this receptor.

Check Digit Verification of cas no

The CAS Registry Mumber 37481-41-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,4,8 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 37481-41:
(7*3)+(6*7)+(5*4)+(4*8)+(3*1)+(2*4)+(1*1)=127
127 % 10 = 7
So 37481-41-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H22N2O/c1-13-6-4-7-14(2)18(13)19(22)20-17-9-5-8-15-12-21(3)11-10-16(15)17/h4-9H,10-12H2,1-3H3,(H,20,22)

37481-41-7Downstream Products

37481-41-7Relevant academic research and scientific papers

Compositions containing 1,2,3,4-tetrahydroisoquinolines used as hypotensive agents

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, (2008/06/13)

Disclosed are 5,6,7 or 8-nuclear substituted benzamido-1,2,3,4-tetrahydroisoquinolines of the formula STR1 in which R is a phenyl containing one to three hydroxyl, nitro, halo, lower alkyl or lower alkoxy groups, and R1 is hydrogen or a lower alkyl. The compounds lower blood pressure in animals.

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