1409976-30-2Relevant academic research and scientific papers
Palladium catalyzed direct α-arylation of α,α- difluoroketones with aryl bromides
Guo, Chen,Wang, Ruo-Wen,Qing, Feng-Ling
, p. 135 - 142,8 (2020/08/20)
The palladium-catalyzed direct α-arylations of α,α- difluoroketones with diverse aryl bromides have been developed by using rac-BINAP as ligand and Cs2CO3 as a mild base in xylene. This method provides an efficient and straightforward access to a variety of α-aryl-α,α-difluoroketones with broad substrate scope.
