141036-93-3

Upstream product

• 75-44-5 phosgene 
• 822-67-3 Cyclohex-2-enol 

Downstream Products

• 141036-95-5 carbonic acid cyclohex-2-enyl ester benzyl ester 
• 925462-20-0 carbonic acid (Z)-2-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-vinyl ester cyclohex-2-enyl ester 
• 925462-21-1 carbonic acid (Z)-2-(tert-butyldimethylsilanyloxy)-1-phenyl-vinyl ester cyclohex-2-enyl ester 

Relevant academic research and scientific papers

Palladium-catalyzed allylic alkylation of carboxylic acid derivatives: N-acyloxazolinones as ester enolate equivalents

Triple A: A general asymmetric allylic alkylation of ester enolate equivalents at the carboxylic acid oxidation state is reported. N-Acylbenzoxazolinone-derived enol carbonates were synthesized and employed in the palladium-catalyzed alkylation reaction. The imide products were readily converted into a series of carboxylic acid derivatives without loss of enantiopurity.

Enantioselective synthesis of α-tertiary hydroxyaldehydes by palladium-catalyzed asymmetric allylic alkylation of enolates

Chiral α-tertiary hydroxyaldehydes are very versatile building blocks in synthetic chemistry. Herein, we report the first examples of a catalytic asymmetric protocol for the synthesis of such compounds from readily available α-halo or α-hydroxy ketones or enol silyl ethers with excellent yields and enantioselectivity. Its synthetic utility is demonstrated in the short, efficient formal synthesis of (S)-oxybutynin. In this process, the chiral ligand controls the regioselectivity as well as the enantioselectivity. Copyright

SYNTHESES DE CARBONATES ET CARBAMATES BENZYLIQUES ET ALLYLIQUES

Different methods for the preparation of carbonates and carbamates derived from 1-phenylethyl, 2-cyclohexenyl and 1-methyl-2-propenyl are described.These conmpounds have been synthesized by the reactions of alcohols, phenols or amines with chloroformiates, imidazolocarbonates or corresponding mixed p-nitrophenylcarbonates. It is shown that these reactions can also be used for the introduction of 1-phenylethyloxycarbonyl - (I), 2-cyclohexenyloxycarbonyl - (II) and 1-methyl-2-propenyloxycarbonyl - (III) groups into alcohols, phenols and amines for the protection of hydroxyls and amino-groups.