141041-83-0Relevant academic research and scientific papers
HETEROARYL COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
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Page/Page column 90, (2010/08/04)
The present invention provides compounds of formula (I) useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf -mediated diseases.
Heterocyclic Compounds Useful as RAF Kinase Inhibitors
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Page/Page column 34, (2009/01/24)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
COMPOUNDS USEFUL AS RAF KINASE INHIBITORS
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Page/Page column 79, (2009/03/07)
The present invention provides compounds useful as inhibitors of Raf protein kinase. The present invention also provides compositions thereof, and methods of treating Raf-mediated diseases.
Dithio and Thiono Esters, 53. Synthesis of N-Protected α-Amino Dithioesters from α-Amino Nitriles and α-Amino Acids
Kohrt, Arne,Hartke, Klaus
, p. 595 - 606 (2007/10/02)
The α-Amino nitriles 1 and 5 have been transformed into the thiolimido ester hydrochlorides 2 and 6 and sulfhydrolyzed to give the N-protected α-amino dithioesters 3 and 7.The α-amino dithioesters 10 were obtained from 1 via the thioamides 8 and their S-a
