141042-21-9 Usage
Description
Cis-2-fluorocyclopropylaminetosylate is an organic compound characterized by the presence of a fluorine atom and a cyclopropyl group. It is a tosylate, derived from toluenesulfonic acid, which is frequently utilized as a protecting group in organic chemistry. The fluorocyclopropyl group endows this compound with unique properties, making it a valuable building block for the synthesis of pharmaceuticals and other organic compounds. The tosylate functional group further enhances its versatility for chemical modifications, establishing cis-2-fluorocyclopropylaminetosylate as a potentially valuable intermediate for synthetic chemistry applications.
Uses
Used in Pharmaceutical Synthesis:
Cis-2-fluorocyclopropylaminetosylate is used as a key intermediate in the synthesis of pharmaceuticals for its ability to influence the properties and reactivity of the target molecules. The fluorine and cyclopropyl groups contribute to the compound's unique characteristics, which are often desirable in drug development.
Used in Organic Chemistry Research:
In the field of organic chemistry, cis-2-fluorocyclopropylaminetosylate is employed as a versatile building block for the development of new organic compounds. Its tosylate functional group provides a convenient handle for further chemical modifications, facilitating the exploration of novel synthetic pathways and the creation of diverse chemical libraries.
Used in Medicinal Chemistry:
Cis-2-fluorocyclopropylaminetosylate is utilized as a structural component in the design of new medicinal agents. The presence of the fluorine atom and the cyclopropyl group can significantly affect the pharmacokinetics and pharmacodynamics of the resulting compounds, potentially leading to improved therapeutic efficacy and selectivity.
Used in Chemical Synthesis Education:
cis-2-fluorocyclopropylaminetosylate serves as an instructive example in educational settings for teaching the principles of organic synthesis, the use of protecting groups, and the influence of functional groups on molecular properties. Its structure and reactivity provide a practical case study for students learning about synthetic strategies and chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 141042-21-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,0,4 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 141042-21:
(8*1)+(7*4)+(6*1)+(5*0)+(4*4)+(3*2)+(2*2)+(1*1)=69
69 % 10 = 9
So 141042-21-9 is a valid CAS Registry Number.
141042-21-9Relevant articles and documents
Synthetic studies on the key component of the new generation of quinolonecarboxylic acid, DU-6859. 1. Synthesis of (1R,2S)-2-fluorocyclopropylamine by the use of optical resolution
Tamura, Osamu,Hashimoto, Masaru,Kobayashi, Yuko,Katoh, Tadashi,Nakatani, Kazuhiko,Kamada, Masahiro,Hayakawa, Isao,Akiba, Toshifumi,Terashima, Shiro
, p. 3889 - 3904 (2007/10/02)
The title synthesis was achieved by employing highly cis-selective cyclopropanation of N-benzyl-N-vinylcarbamates with zinc-monofluorocarbenoid, deprotection of the formed N-benzyl-N-(cis-2-fluorocyclopropyl)carbamates, and optical resolution of the resul
Synthesis and optical resolution of dl-cis-2-fluorocyclopropylamine, the key component of the new generation of quinolonecarboxylic acid, DU-6859
Tamura,Hashimoto,Kobayashi,Katoh,Nakatani,Kamada,Hayakawa,Akiba,Terashima
, p. 3483 - 3486 (2007/10/02)
The title synthesis was accomplished by featuring highly cis-selective cyclopropanation of an N-vinylcarbamate with zinc-monofluorocarbenoid followed by deprotection of the formed N-(cis-2-fluorocyclopropyl)carbamate. Optical resolution of dl-cis-2-fluoro
