141054-41-3Relevant academic research and scientific papers
Et3B-Mediated radical alkylation of pyrroles and indoles
Guerrero, Miguel A.,Miranda, Luis D.
, p. 2517 - 2520 (2006)
An efficient Et3B-mediated oxidative radical substitution of substituted pyrroles and indoles using xanthate based radical chemistry in the presence of iron(II) sulfate is described. Unsubstituted indole gave only low yield or failed in the process. 2-Cyanofuran and 2-benzoylthiophene did not afford the corresponding alkylated products under these conditions.
Efficient, intermolecular, oxidative radical alkylation of heteroaromatic systems under "tin-free" conditions
Osornio, Yazmin M.,Cruz-Almanza, Raymundo,Jimenez-Montano, Vicente,Miranda, Luis D.
, p. 2316 - 2317 (2007/10/03)
Novel and efficient radical alkylation of several heterocyclic systems including pyrroles, indoles, furan and thiophenes is described using xanthate based radical chemistry. The present methodology could be used to provide rapid access to various nonstero
Pyrrole-2,3-quinodimethane Analogues in the Synthesis of Indoles. Part 2. Synthesis and Diels-Alder Reactions of 1,6-Dihydropyranopyrrol-6(1H)-ones
Andrews, John F. P.,Jackson, P. Mark,Moody, Christopher J.
, p. 7353 - 7372 (2007/10/02)
The pyranopyrrol-6-ones 7-9, 12 and 13 are stable cyclic analogues of pyrrole-2,3-quinodimethane, and undergo Diels-Alder reaction with a range of alkynes to give, after loss of carbon dioxide, indoles.
The AlCl3 catalyzed benzoylation of ethyl pyrrole-2-acetate: An unusual 6-substitution
Alexandrou,Rekka,Demopoulos
, p. 761 - 766 (2007/10/02)
In this study, synthetic methodologies have been developed which are potentially useful in preparing 4- and 5-aroylpyrrole-2-acetic acids bearing no alkyl substituents on the heterocyclic nitrogen. These compounds are structurally related to a class of NS
