14109-72-9

Basic information

• Product Name: 1-METHYLTHIO-2-PROPANONE
• Synonyms: (METHYLTHIO)ACETONE;1-METHYLMERCAPTO-2-PROPANONE;1-METHYLTHIO-2-PROPANONE;Acetonyl methyl sulphide;1-Methylthio-2-propanone ((Methylthio)acetone);acetonyl methyl sulfide;1-METHYLTHIO-2-PROPANONE (METHYLTHIO)ACETONE;1-METHYLTHIO-2-PROPANONE, 98+%
• CAS NO: 14109-72-9
• Molecular Formula: C₄H₈OS
• Molecular Weight: 104.17
• EINECS: -0
• Product Categories: sulfide Flavor
• Mol File: 14109-72-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 69-70°C 30mm
• Flash Point: 52°C
• Appearance: /
• Density: 1,023 g/cm3
• Vapor Pressure: 5.19mmHg at 25°C
• Refractive Index: 1.4740
• Water Solubility: Soluble in alcohol and slightly soluble in water.
• BRN: 1737738
• CAS DataBase Reference: 1-METHYLTHIO-2-PROPANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLTHIO-2-PROPANONE(14109-72-9)
• EPA Substance Registry System: 1-METHYLTHIO-2-PROPANONE(14109-72-9)

Safety Data

• Statements: 10
• Safety Statements: 23-24/25
• RIDADR: 1224
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 14109-72-9(Hazardous Substances Data)

Usage

Chemical Properties

1-Methylthio-2-propanone has an odor reminiscent of melon.

Uses

1-Methylthio-2-propanone is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.

InChI:InChI=1/C4H8OS/c1-4(5)3-6-2/h3H2,1-2H3

Upstream product

• 74-93-1 methylthiol 
• 78-95-5 chloroacetone 
• 5188-07-8 sodium thiomethoxide 
• 598-31-2 1-bromoacetone 
• 67-56-1 methanol 
• 22131-92-6 thietane-3-one 
• 603-35-0 triphenylphosphine 
• 673491-82-2 4-(4'-nitrophenyl)-4-hydroxy-1-methylsulfanyl-2-butanone 
• 766546-79-6 4-hydroxy-1-methylsulfanyl-4-phenylbutan-2-one 
• 64127-51-1 4-(methylthio)-3-oxobutanoic acid methyl ester 
• 106-47-8 4-chloro-aniline 
• 13382-53-1 α-methylmercaptopropionamidine 
• 36832-54-9 (2-methoxy-allyl)-dimethyl-sulfonium; bromide 
• 35928-65-5 (methylthio)acetyl chloride 

Downstream Products

• 91157-87-8 4-Hydroxy-3-(methylthio)-3-buten-2-one 
• 31383-34-3 1-methylsulfonyl-2-propanone 
• 766546-79-6 4-hydroxy-1-methylsulfanyl-4-phenylbutan-2-one 
• 850785-54-5 5-chloro-2-methyl-3-(methylthio)-1H-pyrrolo[3,2-b]pyridine 
• 850785-50-1 6-methoxy-2-methyl-3-methylsulfanyl-1H-pyrrolo[2,3-b]pyridine 
• 57330-49-1 2-methyl-6-(trifluoromethoxy)-1H-indole 
• 886436-87-9 2-(4-chlorophenyl)-5-methyl-4-(methylthio)-1,3-oxazole 
• 925418-91-3 2-(1,1-diphenyl-ethyl)-5-methyl-4-methylsulfanyl-oxazole 

Relevant articles and documents

Anomalous Hydrogen-Deuterium Exchange of Cyclic β-Keto Sulfides

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A biocatalytic route to enantioenriched, sulfanyl aldol products

The aldol products derived from sulfur- or selenium containing acceptors were prepared by kinetic resolution in the presence of antibody 84G3 with enantiomeric excesses ranging from 56 to 70%. Much higher level of enantioselectivity was obtained (enantiomeric excesses all superior to 96%) for sulfanyl aldol products derived from thiomethoxyacetone with three different acceptors.

Substituted indoles as alpha-1 agonists

This invention relates to compounds which are alpha-1 receptor agonists, preferably alpha-1A/L receptor agonists, and which are represented by Formula I: wherein X is —S(O)n— or —C(O)—, A is C1-6alkyl, aryl, heteroaryl, hydroxyalkyl,

New hypoxia-selective cytotoxines derived from quinoxaline 1,4-dioxides

A new series of quinoxaline 1,4-dioxides, structurally related to the benzotriazine tirapazamine 1 have been prepared starting from 5,6-dichlorobenzofuroxane 2. The Beirut reaction between 2 and alkyl or aryl thiopropanones afforded the 2-methyl-3-alkyl(a