141104-05-4Relevant articles and documents
Adamantylation and adamantylalkylation of amides, nitriles, and ureas in trifluoroacetic acid
Shokova,Musulu, Tasula,Luzikov,Kovalev
, p. 844 - 856 (2007/10/03)
A new preparative procedure was developed for N-adamantylation of carboxylic acids amides and ureas, and C5-adamantylation of barbituric acid in trifluoroacetic acid medium with tertiary adamantanols and 1-adamantylalkanols. The reaction of 2-adamantanols and secondary 1-adamantylalkanols with nitriles was for the first time used in the preparation of W-(2-adamantyl)-and N-(1-adamantylalkyl)amides.