141116-75-8

Upstream product

• 141045-58-1 (R)-(+)-2-methyl-2-(4-methylphenyl)-3-<<(4-methylphenyl)sulfonyl>hydrazono>-4-butanolide 
• 133678-80-5 (R)-(+)-methyl 4-diazo-2-methyl-2-(4-methylphenyl)-3-oxobutanoate 
• 141045-62-7 (S)-(+)-methyl 2-(chloroformyl)-2-(4-methylphenyl)propionate 
• 877077-49-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methylphenyl)propionic acid 
• 127047-04-5 dimethyl 2-methyl-2-(4-methylphenyl)malonate 
• 79443-97-3 methyl 2-(4-methylphenyl)propanoate 
• 133678-83-8 (R)-(+)-2-methyl-2-(4-methylphenyl)-3-oxo-4-butanolide 

Relevant academic research and scientific papers

Asymmetric Construction of Quaternary Carbons from Chiral Malonates: Selective and Versatile Total Syntheses of the Enantiomers of α- and β-Cuparenones from a Common Optically Active Precursor

From a single chiron (R)-4, available with high enantiomeric purity (96percent) by simple enzymatic hydrolysis (PLE) of a prochiral malonate, were prepared convenient precursors of the two enantiomers of α- and β-cuparenones (1a,b and 2a,b).This versatile