141177-79-9

Basic information

• Product Name: Thiazole, 4-(4-methylphenyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-
• CAS NO: 141177-79-9
• Molecular Formula: C15H12F3N3S
• Molecular Weight: 323.342
• Mol File: 141177-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thiazole, 4-(4-methylphenyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiazole, 4-(4-methylphenyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-(141177-79-9)
• EPA Substance Registry System: Thiazole, 4-(4-methylphenyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-(141177-79-9)

Safety Data

• Hazardous Substances Data: 141177-79-9(Hazardous Substances Data)

Upstream product

• 4872-78-0 2-hydrazino-4-(4'-tolyl)thiazole 
• 367-57-7 1,1,1-Trifluoro-2,4-pentanedione 

Relevant articles and documents

Reaction of hetarylhydrazines with 1,1,1-trifluoropentane-2,4-dione and ethyl 2,4-dioxovalerate

The reaction of 2-hydrazino-4-(4'-substitutedphenyl)thiazoles with 1,1,1-trifluoropentane-2,4-dione (1) gives the isomeric 5(3)-trifluoromethyl-3(5)-methyl-1-pyrazoles (3 and 4).A similar reaction of 2-hydrazinobenzothiazoles with ethyl 2,4-dioxovalerate (2) furnishes the isomeric-1-(6'-H/methylbenzothiazol-2'-yl)-5(3)-ethoxycarbonyl-3(5)-methylpyrazoles (8 and 10).However, the reaction of 2-hydrazinobenzothiazoles with 1 gives 1-(6'-substitutedbenzothiazol-2'-yl)-5-trifluoromethyl-3-methylpyrazoles (5) as the sole products.The intermediate 5-hydroxy-2-pyrazolines (6) have been isolated and characterised.The structure of the isomeric pyrazoles have been established on the basis of their NMR (1H and 13C) spectra.