141196-84-1Relevant articles and documents
Structure-activity relationships among a new class of antiviral heterosubstituted 2',3'-dideoxynucleoside analogues
Mansour,Jin,Wang,Dixit,Evans,Tse,Belleau,Gillard,Hooker,Ashman,Cammack,Salomon,Belmonte,Wainberg
, p. 627 - 635 (1995)
3'-Oxa-4'-thiocytidine nucleoside analogues 14-17 were prepared from oxathiolanes 10 and 11, and evaluated for activity against HIV-1 and HBV in vitro. The nucleoside analogues were found to possess potent activities against HIV-1 in a panel of cell lines. Compound 16 is moderately active against HBV in 2.2.15 cells.