1412-19-7

Usage

Uses

Used in Histology:
HEMATOXYLIN is used as a staining agent for promoting the visualization and localization of the colored end product in immunohistochemical (IHC) procedures.
Used in Microscope Slide Preparations:
HEMATOXYLIN is used as a counterstain to stain nuclei in microscope slide preparations in histology, often in combination with eosin to form the hematoxylin and eosin (H&E) stain. This stain is a permanent alternative to temporary stains.
Used in Ink Manufacturing:
HEMATOXYLIN is used in the manufacture of ink due to its inherent properties.

References

https://en.wikipedia.org/wiki/Haematoxylin https://pubchem.ncbi.nlm.nih.gov/compound/442514#section=Chemical-Vendors http://www.leicabiosystems.com/ihc-ish-fish/immunohistochemistry-ihc-antibodies-novocastra-reagents/detection-systems-buffers/products/hematoxylin/ http://www.leicabiosystems.com/pathologyleaders/the-basic-chemistry-of-hematoxylin/ https://www.ncbi.nlm.nih.gov/pubmed/16195172

InChI:InChI=1/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

Upstream product

• 171231-54-2 (-)-3-hydroxy-7,8-dibenzyloxy-3-(3',4'-dibenzyloxybenzyl)-2,3-dihydro-4H-1-benzopyran-4-one 
• 1027991-60-1 7,8-dibenzyloxy-3-(3',4'-dibenzyloxybenzyl)-2,3-dihydro-4H-1-benzopyran-4-one 
• 171231-55-3 (-)-haematoxylin tetrabenzyl ether 
• 171015-84-2 7,8-dihydroxy-3-(3',4'-dihydroxybenzyl)-2,3-dihydro-4H-1-benzopyran-4-one 
• 1621-47-2 7,8-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one 
• 5447-02-9 3,4-dibenzyloxybenzaldehyde 

Downstream Products

• 1360437-07-5 C₂₆H₂₄O₅ 
• 1360437-06-4 C₂₇H₂₃F₃O₈S 
• 1360437-02-0 C₂₆H₂₄O₆ 
• 1360437-01-9 C₂₆H₂₄O₆ 
• 1360437-17-7 C₂₆H₂₄O₅ 
• 1360437-13-3 C₂₇H₂₃F₃O₈S 

Related news

A study of the electrochemical behavior of HEMATOXYLIN (cas 1412-19-7) as an important bioactive flavonoid09/30/2019

The electrochemical oxidation of hematoxylin, as an important biological molecule, was studied using cyclic voltammetry. In this study, the effect of different parameters such as pH, hematoxylin concentration, and time window of the chosen electrochemical method has been used for understanding t...detailed

Regular articleReliable Gene Expression Profiling from Small and HEMATOXYLIN (cas 1412-19-7) and Eosin–Stained Clinical Formalin-Fixed, Paraffin-Embedded Specimens Using the HTG EdgeSeq Platform09/29/2019

Clinical biomarker studies are often hindered by the scarcity or suboptimal quality of biological specimens. EdgeSeq, a transcriptomics analysis platform, combines quantitative nuclease protection assay technology with next-generation sequencing, using small amounts of starting material and deli...detailed

Adsorption and deposition-assisted anodic stripping voltammetry for determination of antimony(III) in presence of HEMATOXYLIN (cas 1412-19-7) on glassy carbon electrode09/28/2019

A validated simple, reliable and sensitive adsorptive anodic stripping voltammetric procedure is suggested for the accurate determination of antimony(III) on a glassy carbon electrode (GCE) in the presence of hematoxylin (HT), used as a chemical receptor in antimony analysis for the first time. ...detailed

Full paperRotational wind power triboelectric nanogenerator using aerodynamic changes of friction area and the adsorption effect of HEMATOXYLIN (cas 1412-19-7) onto feather based on a diversely evolved hyper-branched structure09/27/2019

In the present study, a feather rotating-TENG (FTR-TENG) was developed by analyzing the properties of nanostructure and changes in friction areas by the aerodynamic motion of naturally evolved feathers. The motion and area of surface of the feathers vary according to the interlocking effect of t...detailed

Review articleThe HEMATOXYLIN (cas 1412-19-7) and eosin stain in anatomic pathology—An often-neglected focus of quality assurance in the laboratory09/24/2019

Accuracy in morphological diagnosis is the cornerstone of anatomic pathology. Proficiency with the microscope offers values to the health care system that cannot be overestimated. However, that skill is only possible if high-quality histological substrates are available for assessment, particula...detailed

Relevant academic research and scientific papers

Synthesis and sweet taste of optically active (-)-haematoxylin and of some (+/-)-haematoxylin derivatives

In order to explain the sweet taste of the natural polyphenolic compound (+)-haematoxylin 1, four (+/-)-haematoxylin derivatives 4-7 and the enantiomer (-)-haematoxylin have been synthesized and tasted.Unlike haematoxylin, the derivatives 4-7 have a restr

The Reaction of Hematoxylin with Zirconyl Chloride Studied Spectrophotometrically

The reaction of hematoxylin with zirconyl chloride in acid solutions was studied spectrophotometrically.A strong absorption band with λmax = 525 nm is attributed to a loose complex formed between hemateine and zirconium(IV) ions.The experimental findings - especially the fact that the linear absorption coefficient increases with time, passes through a maximum and then declines exponentially - are consistent with a four step mechanism.Two of the steps are fast equilibria, while the other two are slow dissociation reactions, the second being an order of magnitude faster than the first.The rate constants for the slow steps and the equillibrium constants for the fast steps have been determined.From the variation of these constants with temperature the activation parameters of the slow reactions and thermodynamic data for the fast equilibria have been calculated.Also the molar absorption coefficient of the absorbing complex has been estimated.Possible analytical applications of the reactions studied are briefly discussed. - Keywords: Zirconyl chloride, Hematoxylin complex formation rates, Activation parameters of complexes, Thermodynamic data of complexes