1412410-76-4Relevant academic research and scientific papers
Heck cross-coupling reactions in ionic liquid mediated pd nanocatalysts
Gautam, Prashant,Srivastava, Vivek
, p. 359 - 372 (2021/09/07)
We straightforwardly synthesized 18 different types of palladium nanoparticles by using a series of palladium metal precursors and ionic liquids. All the materials went for XRD, TEM, and ICP-OES analysis, before going to Heck cross-coupling reaction as a catalyst. We evaluated the catalytic performance of our developed IL#Pd MNP catalyst over Heck cross-coupling reaction between different terminal olefins with various 3-iodo-benzopyrones, including sterically hindered, electron-rich, electron neutral and electron-deficient systems. We obtained the Heck cross-coupling reaction product in good to average yield under phosphine free reaction condition with an added advantage of 6 times catalyst recycling.
Anti-hepatitis B virus and anti-cancer activities of novel isoflavone analogs
Zhang, Yikai,Zhong, Hanyu,Lv, Zhiliang,Zhang, Mingfeng,Zhang, Tao,Li, Qisheng,Li, Ke
, p. 158 - 167 (2013/05/09)
We have synthesized a series of novel isoflavone analogs and evaluated their anti-HBV and anti-cancer activities in vitro. The bioassays showed that the majority of the resultant compounds exerted inhibitory effects on HBsAg and HBeAg levels, HBV DNA replication, as well as the growth of four human cancer cell lines to various extents, which supported the rationale of the design. In particular, compound 8f showed the highest activity against HBV infection and HBV-related liver cancer. Compound 7l (IC50 = 0.47 μM) also exerted remarkable inhibitory effect on the growth lung cancer cell line A-549.
Efficient Heck cross-coupling of 3-iodo-benzopyrones with olefins under microwave irradiation without phosphine
Zhang, Yikai,Lv, Zhiliang,Zhong, Hanyu,Zhang, Mingfeng,Zhang, Tao,Zhang, Wannian,Li, Ke
, p. 9777 - 9787 (2012/11/07)
An efficient and effective microwave-assisted Heck cross-coupling of different terminal olefins with various 3-iodo-benzopyrones including sterically hindered, electron-rich, electron-neutral, and electron-deficient is developed. It proceeded faster and g
