141245-75-2

Upstream product

• 2585-28-6 N-(2-chlorophenyl)-4-nitrobenzamide 
• 122-04-3 4-nitro-benzoyl chloride 
• 95-51-2 o-chloroaniline 

Downstream Products

• 141245-73-0 2-(4-aminophenyl)-7⁽⁴⁾-chloro-6⁽⁵⁾-aminobenzimidazole 
• 141245-81-0 2-(4-acetamidophenyl)-7⁽⁴⁾-chlorobenzimidazole 
• 141245-79-6 2-(4-aminophenyl)-7⁽⁴⁾chloro-6⁽⁵⁾nitrobenzimidazole 
• 141245-83-2 2-(4-acetamidophenyl)-7⁽⁴⁾-chloro-6⁽⁵⁾-nitrobenzimidazole 
• 141245-78-5 4-(7-chloro-1H-benzo[d]imidazol-2-yl)aniline 

Relevant academic research and scientific papers

SYNTHESIS AND STRUCTURE OF MONOCHLORO DERIVATIVES OF 2-(4-AMINOPHENYL)-5(6)-AMINOBENZIMIDAZOLE

Methods for the production of the monochloro derivatives of 2-(4-aminophenyl)-5(6)-aminobenzimidazole from chloronitrobenzanilides or by the condensation of 1,2,4-triaminobenzene with chloroaminobenzoic acid were investigated.It was established that the nitration of o-chlorobenzanilides takes place selectively in a mixture of acetic acid, acetic anhydride, and chloroform, while the nitration of 4(7)- or 5(6)-chlorobenzimidazoles takes place in sulfuric acid.The effect of the chlorine atoms and the nitro (amino) group on the IR and PMR spectra of the benzanilides and benzimidazoles is determined by their mutual position and by the position in relation of the amide bridge or the condensed imidazole ring.Analysis of the PMR spectra of the chlorodiaminophenylbenzimidazoles indicated that the amino group was localized at position 6 of the benzimidazole ring.