141310-65-8

Basic information

• Product Name: 4'-{{4-butyl-2-methyl-6-[2-(methylthio)ethoxy]pyrimidin-5-yl}methyl}-[1,1-biphenyl]-2-carbonitrile
• CAS NO: 141310-65-8
• Molecular Weight: 431.602
• Mol File: 141310-65-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4'-{{4-butyl-2-methyl-6-[2-(methylthio)ethoxy]pyrimidin-5-yl}methyl}-[1,1-biphenyl]-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-{{4-butyl-2-methyl-6-[2-(methylthio)ethoxy]pyrimidin-5-yl}methyl}-[1,1-biphenyl]-2-carbonitrile(141310-65-8)
• EPA Substance Registry System: 4'-{{4-butyl-2-methyl-6-[2-(methylthio)ethoxy]pyrimidin-5-yl}methyl}-[1,1-biphenyl]-2-carbonitrile(141310-65-8)

Safety Data

• Hazardous Substances Data: 141310-65-8(Hazardous Substances Data)

Upstream product

• 137860-02-7 2-(2'-Cyano-biphenyl-4-ylmethyl)-3-oxo-heptanoic acid ethyl ester 
• 135689-65-5 4'-<(6-butyl-1,4-dihydro-2-methyl-4-oxo-5-pyrimidinyl)methyl><1,1'-biphenyl>-2-carbonitrile 
• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 7737-62-4 Ethyl 3-oxoheptanoate 
• 5271-38-5 2-methylmercapto-ethanol 
• 135689-70-2 4'-(4-Butyl-6-chloro-2-methyl-pyrimidin-5-ylmethyl)-biphenyl-2-carbonitrile 

Relevant articles and documents

COMPOUND CONTAINING A NOVEL 4-ALKOXYPYRIMIDINE STRUCTURE AND MEDICINE CONTAINING SAME

Disclosed is novel compound and medicinal formulation containing same, possessing both angiotensin II receptor blocking and PPARγ activation effect, of use as a medicine for prevention and/or treatment of hypertension, heart disease, angina pectoris, cerebrovascular disorder, cerebral circulatory disturbances, post-ischemic peripheral circulatory damage, renal disease, arteriosclerosis, inflammatory disorder, type 2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinaemia. Further disclosed is the general formula I (where one or both of R1 and R2 represent a C1-6 alkyl group, R3 represents a C1-6 alkyl group which may contain one or more substituent groups selected from group A, or a C3-8 cycloalkyl group which may contain one or more substituent groups selected from group B.) which represents the compound, and salts thereof, solvates thereof, and medicinal compositions containing any of these.