141355-50-2Relevant academic research and scientific papers
The First Asymmetric Total Synthesis of Thienamycin-like γ-Lactam and its Analogue
Nagao, Yoshimitsu,Matsunaga, Hiroshi,Kumagai, Toshio,Inoue, Yoshinori,Miwa, Yoshihisa,Taga, Tooru
, p. 437 - 439 (2007/10/02)
The asymmetric total synthesis of thienamycin-like γ-lactam 1 and its analogue 2 has been accomplished by utilising highly diastereoselective alkylation of tin(II) enolate 5 on acyl imine obtained in situ from chiral 3-substituted 5-acetoxypyrrolidin-2-on
