141380-89-4

Upstream product

• 33109-58-9 succinic acid bis(p-nitrophenyl ester) 
• 141380-88-3 [(S)-2-(4-Amino-butyl)-4,7,10-tris-(hydroxy-methyl-phosphinoylmethyl)-1,4,7,10-tetraaza-cyclododec-1-ylmethyl]-methyl-phosphinic acid 
• 123472-54-8 (+)-(2S)-2-(4-benzamidobutyl)-1,4,7,10-tetra-azacyclododecane 
• 132610-06-1 [(S)-2-(4-Benzoylamino-butyl)-4,7,10-tris-(ethoxy-methyl-phosphinoylmethyl)-1,4,7,10-tetraaza-cyclododec-1-ylmethyl]-methyl-phosphinic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis of new macrocyclic amino-phosphinic acid complexing agents and their C- and P-functionalised derivatives for protein linkage

The synthesis of various macrocyclic complexing agents with alkyl- and arylphosphinic substituents is reported together with their C- and N-functionalised analogues as active esters suitable for antibody conjugation.