1413875-84-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 23511-05-9 toluene-4-sulfonic acid 1,4-dioxa-spiro[4.5]dec-8-yl ester 
• 183208-35-7 5-bromo-1H-pyrrolo[2,3-b]pyridine 
• 261762-39-4 2-chloro-3,6-difluorobenzaldehyde 
• 202925-07-3 2-chloro-1-fluoro-4-methoxybenzene 
• 1175275-29-2 4-iodo-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazole 
• 1227611-94-0 4-(4-iodo-1H-pyrazol-1-yl)cyclohexanone 
• 1350322-49-4 5-bromo-3-[(2-chloro-3-fluoro-6-methoxyphenyl)-hydroxymethyl]-1H-pyrrolo[2,3-b]pyridine 
• 1263378-40-0 2-chloro-3-fluoro-6-methoxy-benzaldehyde 
• 1257997-18-4 1-(trans-4-{[tert-Butyl(dimethyl)silyl]oxy}cyclohexyl)-4-iodo-1H-pyrazole 
• 1227611-92-8 4-(4-iodo-1H-pyrazol-1-yl)cyclohexanol 
• 1257997-17-3 1-((1r,4r)-4-((tert-butyl dimethyl silyl)oxy)cyclo hexyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1413875-90-7 5-bromo-3-[1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoro-2,2-bis(phenylsulfonyl)ethyl]-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1413875-80-5 trans-4-(4-{3-[-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 
• 1413876-13-7 C₃₁H₃₉ClF₂N₄O₂Si 
• 1413868-51-5 trans-4-(4-{3-[(1S)-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 
• 1413868-46-8 trans-4-(4-{3-[(1R)-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 

Relevant academic research and scientific papers

FUSED BICYCLIC KINASE INHIBITORS

Compounds of Formula (I), pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of MET, RON, ALK, IR, or IGF-1R. This Abstract is not limiting of the invention.