1257997-18-4

Usage

Pyrazole derivative

A chemical compound derived from the pyrazole ring structure.

Explanation

Pyrazole is a five-membered heterocyclic compound containing two nitrogen atoms. 1-(trans-4-{[tert-Butyl(dimethyl)silyl]oxy}cyclohexyl)-4-iodo-1H-pyrazole is a derivative, meaning it has been modified from the basic pyrazole structure.

Explanation

The cyclohexyl ring is a part of the compound's structure, consisting of six carbon atoms connected in a ring formation.

Explanation

This group consists of a silicon atom bonded to a tert-butyl group (a carbon chain with a branching structure) and two methyl groups (each containing one carbon and three hydrogen atoms). The silicon atom is also connected to an oxygen atom, which is bonded to the fourth carbon atom of the cyclohexyl ring.

Explanation

The iodine atom is a halogen that is covalently bonded to the fourth position of the pyrazole ring, adding to the compound's chemical complexity.

Explanation

The compound's unique structural features make it a candidate for use in various fields, including the synthesis of organic compounds, development of pharmaceutical drugs, and creation of new materials with specific properties.

Explanation

Due to its unique structure and potential applications, 1-(trans-4-{[tert-Butyl(dimethyl)silyl]oxy}cyclohexyl)-4-iodo-1H-pyrazole is considered a valuable subject for further research and development to explore its properties and possible uses in various industries.

Cyclohexyl ring

A six-membered carbon ring with a specific arrangement of atoms.

tert-Butyl(dimethyl)silyloxy group

A functional group attached to the fourth carbon atom of the cyclohexyl ring.

Iodine atom

Present at the fourth position of the pyrazole ring.

Potential applications

Organic synthesis, pharmaceuticals, and materials science.

Research and development

Interesting target for further study.

Upstream product

• 1227611-92-8 4-(4-iodo-1H-pyrazol-1-yl)cyclohexanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1227611-94-0 4-(4-iodo-1H-pyrazol-1-yl)cyclohexanone 
• 1175275-29-2 4-iodo-1-(1,4-dioxaspiro[4.5]decan-8-yl)-1H-pyrazole 
• 23511-05-9 toluene-4-sulfonic acid 1,4-dioxa-spiro[4.5]dec-8-yl ester 

Downstream Products

• 1350324-56-9 1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-4-iodo-5-(d3)methyl-1H-pyrazole 
• 1350324-25-2 1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-4-iodo-5-methyl-1H-pyrazole 
• 1257997-17-3 1-((1r,4r)-4-((tert-butyl dimethyl silyl)oxy)cyclo hexyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 1413875-80-5 trans-4-(4-{3-[-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 
• 1413875-84-9 5-[1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-1H-pyrazol-4-yl]-3-[1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoro-2,2-bis(phenylsulfonyl)ethyl]-1H-pyrrolo[2,3-b]pyridine 
• 1413876-13-7 C₃₁H₃₉ClF₂N₄O₂Si 
• 1413868-51-5 trans-4-(4-{3-[(1S)-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 
• 1413868-46-8 trans-4-(4-{3-[(1R)-1-(2-chloro-3-fluoro-6-methoxyphenyl)-2-fluoroethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazol-1-yl)cyclohexanol 
• 1413876-18-2 trans-4-[4-(3-{-1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl]-2-fluoroethyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl]cyclohexanol 
• 1413875-95-2 trans-4-[4-(3-{-1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl]-2-fluoroethyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl]cyclohexanol 
• 1413875-99-6 5-[1-(trans-4-{[tert-butyl(dimethyl)silyl]oxy}cyclohexyl)-1H-pyrazol-4-yl]-3-{1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl]-2-fluoro-2,2-bis(phenylsulfonyl)ethyl}-1H-pyrrolo[2,3-b]pyridine 
• 1413868-61-7 trans-4-[4-(3-{(1S)-1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl]-2-fluoroethyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl]cyclohexanol 
• 1413868-56-0 trans-4-[4-(3-{(1R)-1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl]-2-fluoroethyl}-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazol-1-yl]cyclohexanol 
• 1350425-15-8 trans-4-(4-{3-[(1S)-1-[2-chloro-6-(difluoromethoxy)-3-fluorophenyl](1-2H)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-5-methyl-1H-pyrazol-1-yl)cyclohexanol 

Relevant academic research and scientific papers

FUSED BICYCLIC KINASE INHIBITORS

Compounds of Formula (I), pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of MET, RON, ALK, IR, or IGF-1R. This Abstract is not limiting of the invention.

Fused Bicyclic Kinase Inhibitors

Compounds of Formula I, as shown below and defined herein: pharmaceutically acceptable salts thereof, synthesis, intermediates, formulations, and methods of disease treatment therewith, including treatment of cancers, such as tumors driven at least in part by at least one of RON, MET or ALK. This Abstract is not limiting of the invention.