1413940-37-0Relevant articles and documents
Synthesis and biological characterization of a series of novel diaryl amide M1 antagonists
Poslusney, Michael S.,Sevel, Christian,Utley, Thomas J.,Bridges, Thomas M.,Morrison, Ryan D.,Kett, Nathan R.,Sheffler, Douglas J.,Niswender, Colleen M.,Daniels, J. S.,Conn, P. J.,Lindsley, Craig W.,Wood, Michael R.
, p. 6923 - 6928,6 (2020/09/02)
Utilizing a combination of high-throughput and multi-step synthesis, SAR in a novel series of M1 acetylcholine receptor antagonists was rapidly established. The efforts led to the discovery the highly potent M1 antagonists 6 (VU04312