36854-27-0Relevant articles and documents
Analysis of the 13C and 1H Spectra of Mixtures of Benzylidene Derivatives
Bradley, J. C.,Williams, A. J.
, p. 496 - 498 (1994)
The 1H and 13C NMR spectra of methyl (E)-2,3-diphenylprop-2-enoate and methyl (E)-2-(2-phenylethenyl)benzoate resulting from the electrocyclic ring opening of benzocyclobutenone starting materials have been assigned.A combination of direct detection 2D NMR techniques, COSY, HETCOR, and FLOCK, provided the assignments of the 1H and 13C resonances. - Keywords: NMR 1H NMR 13C NMR Benzylidene derivatives
Magnesium chloride (MgCl2) catalyzed highly regioselective C-3 ring opening of 2,3 epoxy alcohols by N-nucleophile
Kumar, Amit,Panda, Gautam
supporting information, (2021/04/09)
We herein report Magnesium chloride (MgCl2) catalyzed first highly C3-selective ring-opening reaction of various 2,3-epoxy alcohols with assorted N-Nucleophiles and sodium azide to furnish 3-amino-1,2 diols and 3-azido-1,2 diols respectively in high yields under mild reaction conditions. This protocol attributes the use of catalytic amount of Magnesium chloride (MgCl2), simple reaction conditions, practical operation and broad functional group tolerance.
Oxiranyl remote anions from epoxy cinnamates and their application towards the synthesis of α,β-epoxy-γ-butyrolactones
Sermmai, Patpanat,Ruangsupapichat, Nopporn,Thongpanchang, Tienthong
supporting information, (2020/11/19)
A series of α,β-epoxy-γ-butyrolactones were synthesized in moderate yields via oxiranyl remote anions derived from epoxy cinnamate esters. The key synthetic step involved deprotonation of the β-position of α,β-epoxy cinnamate derivatives where the generated β-anion was stabilized by remote chelation from an ester group. The substitution reaction of the anion with a variety of ketones, followed by cyclization, readily furnished the desired substituted α,β-epoxy-γ-butyrolactones.
