1414368-49-2

Upstream product

• 6140-63-2 1-methyl-1-cyclopentanecarbaldehyde 
• 218273-62-2 C₁₉H₁₆O₄S₂ 
• 1414368-30-1 1-(1-methylcyclopentyl)-3,5,5-tris(phenylsulfonyl)octa-1,2-dien-7-yne 

Relevant academic research and scientific papers

Csp3-Csp3 and C sp3-H bond activation of 1,1-disubstituted cyclopentane

The unprecedented Csp3-Csp3 bond cleavage of unactivated cyclopentane has been achieved. Rh I-catalyzed cycloaddition of allenylcyclopentane-alkynes produced in situ the 9-cyclopentyl-8-rhodabicyclo[4.3.0]nona-1,6-diene intermediates, which subsequently underwent [7+2] cycloaddition via β-C elimination, affording bicyclo[7.4.0]tridecatriene derivatives in good yields. Changing the Rh I catalyst effected the Cγ-H bond activation of the common 9-cyclopentyl-8-rhodabicyclo[4.3.0]nona-1,6-diene intermediate to produce the novel spiro[2.4]heptane skeleton in a site-selective manner.