1414377-68-6Relevant articles and documents
Aziridine-2-carboxaldehyde dimers undergo homo-Ugi 4-component-5-center reactions
Rotstein, Benjamin H.,Yudin, Andrei K.
, p. 2851 - 2858 (2012)
Dimeric α-aziridine aldehydes have been used as the aldehyde component in Ugi and Passerini reactions. The highly reactive mixed anhydride intermediate is subject to nucleophilic attack by the aziridine, leading to homo-Ugi' β-acylaziridinyl-α-aminoamides. The products can be readily transformed into substituted lactones. Georg Thieme Verlag Stuttgart ? New York.