1414381-84-2Relevant academic research and scientific papers
Efficient Synthesis of Functionalized Pyrido[2,3- c ]coumarin Derivatives by a One-Pot Three-Component Reaction
Chen, Zhiwei,Hu, Lele,Peng, Fei
, p. 1888 - 1892 (2016/07/16)
A methanesulfonic acid promoted three-component reaction has been developed for the synthesis of functionalized pyrido[2,3-c]coumarin derivatives from ketones, aromatic aldehydes, and 3-aminocoumarin. In this simple and efficient protocol, products were obtained in moderate to good yields (28 examples). The reaction proceeds by an asynchronous [4+2] cycloaddition (inverse-electron-demand Diels-Alder reaction).
A simple and expedient synthesis of functionalized pyrido[2,3-c] coumarin derivatives using molecular iodine catalyzed three-component reaction
Khan, Abu T.,Das, Deb K.,Islam, Kobirul,Das, Pradipta
, p. 6418 - 6422,5 (2012/12/12)
A wide variety of substituted pyrido[2,3-c] coumarin derivatives have been accomplished from 3-aminocoumarins, aromatic aldehydes, and alkynes in the presence of 10 mol % molecular iodine in acetonitrile under reflux conditions through one-pot Povarov reactions. Good yields, no need of aqueous work-up procedure and chromatographic separation, environmentally benign are some of the salient features of the present protocol.
A simple and expedient synthesis of functionalized pyrido[2,3-c] coumarin derivatives using molecular iodine catalyzed three-component reaction
Khan, Abu T.,Das, Deb K.,Islam, Kobirul,Das, Pradipta
, p. 6418 - 6422 (2013/01/15)
A wide variety of substituted pyrido[2,3-c] coumarin derivatives have been accomplished from 3-aminocoumarins, aromatic aldehydes, and alkynes in the presence of 10 mol % molecular iodine in acetonitrile under reflux conditions through one-pot Povarov reactions. Good yields, no need of aqueous work-up procedure and chromatographic separation, environmentally benign are some of the salient features of the present protocol.
