1414494-75-9Relevant academic research and scientific papers
Diastereoselective reductive ring expansion of spiroketal dihydropyranones to cis -fused bicyclic ethers
Zhu, Liangyu,Song, Liyan,Tong, Rongbiao
, p. 5892 - 5895 (2012)
A novel double cascade synthetic strategy was developed for the diastereoselective syntheses of cis-fused bicyclic ethers, featuring cascade Achmatowicz rearrangement/spiroketalization and cascade spiroketal reduction/oxa-Michael cyclization. Especially, the chemo-, regio-, and diastereoselective reduction of densely functionalized spiroketal dihydropyranones, followed by oxa-Michael cyclization in a one-pot fashion, was achieved.
