1414575-97-5

Basic information

• Product Name: 3-((2,2-dimethyl-1,3-dioxan-5-yl)methoxy)-4-methyl-1-phenyl-1H-pyrazol-5-amine
• Synonyms: 3-((2,2-dimethyl-1,3-dioxan-5-yl)methoxy)-4-methyl-1-phenyl-1H-pyrazol-5-amine
• CAS NO: 1414575-97-5
• Molecular Weight: 317.388
• Mol File: 1414575-97-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((2,2-dimethyl-1,3-dioxan-5-yl)methoxy)-4-methyl-1-phenyl-1H-pyrazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((2,2-dimethyl-1,3-dioxan-5-yl)methoxy)-4-methyl-1-phenyl-1H-pyrazol-5-amine(1414575-97-5)
• EPA Substance Registry System: 3-((2,2-dimethyl-1,3-dioxan-5-yl)methoxy)-4-methyl-1-phenyl-1H-pyrazol-5-amine(1414575-97-5)

Safety Data

• Hazardous Substances Data: 1414575-97-5(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 77-76-9 2,2-dimethoxy-propane 
• 4728-12-5 2,2-dimethyl-5-hydroxymethyl-1,3-dioxane 
• 934397-98-5 5-amino-4-methyl-1-phenyl-1H-pyrazol-3(2H)-one 
• 131372-64-0 (2,2-dimethyl-1,3-dioxan-5-yl)methyl methanesulfonate 

Downstream Products

• 1414575-99-7 phenyl (3-(3-hydroxy-2-(hydroxymethyl)propoxy)-4-methyl-1-phenyl-1H-pyrazol-5-yl)carbamate 
• 1610529-13-9 1-(3-(3-hydroxy-2-(hydroxymethyl)propoxy)-4-methyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-phenyl-8-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)urea 

Relevant articles and documents

BICYCLIC HETEROARYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

Compounds of Formula I or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.