1414809-22-5Relevant academic research and scientific papers
Palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides to give 4-amine-benzo[b][1,4]oxazepines
Liu, Bifu,Li, Yibiao,Yin, Meizhou,Wu, Wanqing,Jiang, Huanfeng
supporting information, p. 11446 - 11448 (2013/01/15)
A robust route to 4-amine-benzo[b][1,4]oxazepines relying upon a palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides has been developed. This chemistry presumably proceeds through the migratory insertion of isocyanides into the vinyl-palladium intermediate as a key step.
