1414847-25-8

Basic information

• Product Name: C₃₆H₄₅N₃O₄S
• Synonyms: C₃₆H₄₅N₃O₄S
• CAS NO: 1414847-25-8
• Molecular Weight: 615.837
• Mol File: 1414847-25-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₅N₃O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₅N₃O₄S(1414847-25-8)
• EPA Substance Registry System: C₃₆H₄₅N₃O₄S(1414847-25-8)

Safety Data

• Hazardous Substances Data: 1414847-25-8(Hazardous Substances Data)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 316-42-7 emetine dihydrochloride 

Relevant articles and documents

EMETINE DERIVATIVES, PRODRUGS CONTAINING SAME, AND METHODS OF TREATING CONDITIONS USING SAME

Compounds are provided herein which are emetine derivatives that can be used as prodrugs which selectively undergo activation to release emetine in specific cellular conditions. In one aspect, a blocking group is incorporated onto the emetine molecule by the derivization of the N2'-position with moieties that can be selectively removed by hydrolysis in the cancer/tumor microenvironment. Such compounds are less cytotoxic than emetine and are substantially inactive in non-cancerous cells. In one aspect, the compounds described herein can be used for the treatment of metastatic and non-metastatic cancers, including, for example, breast cancer, prostate cancer, lung cancer, and leukemia.