1414875-57-2

Upstream product

• 1357098-10-2 4-chloro-1-(difluoromethyl)-N-methoxy-N-methyl-1H-pyrazole-3-carboxamide 
• 1357098-11-3 4-chloro-1-(difluoromethyl)-1H-pyrazole-3-carbaldehyde 
• 1301740-78-2 (S)-4-(5-amino-2-fluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-oxazin-2-amine 
• 1310351-06-4 4-chloro-1-difluoromethyl-1H-pyrazole-3-carboxylic acid methyl ester 
• 1310351-03-1 1-difluoromethyl-1H-pyrazole-3-carboxylic acid methyl ester 
• 1310350-99-2 4-chloro-1-(difluoromethyl)-1H-pyrazole-3-carboxylic acid 
• 925179-02-8 1-(difluoromethyl)-1H-pyrazole-3-carboxylic acid 

Relevant academic research and scientific papers

1,3-OXAZINES AS BACE1 AND/OR BACE2 INHIBITORS

The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present inv

1,3-OXAZINES AS BACE 1 AND/OR BACE2 INHIBITORS

The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present inv