1414889-36-3

Upstream product

• 497235-37-7 6-chloro-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)hydroquinazolin-2-one 
• 1414889-08-9 (R)-6-chloro-1-(4-methoxybenzyl)-2-oxo-4-(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile 

Downstream Products

• 214287-99-7 (S,E)-6-chloro-4-(2-cyclopropylvinyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1414889-37-4 (S,Z)-6-chloro-4-(2-cyclopropylvinyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1360591-23-6 (S,E)-6-chloro-4-(2-cyclopropylvinyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 

Relevant academic research and scientific papers

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. This journal is

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. The Royal Society of Chemistry 2012.