1414889-08-9

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 497235-37-7 6-chloro-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)hydroquinazolin-2-one 

Downstream Products

• 214287-99-7 (S,E)-6-chloro-4-(2-cyclopropylvinyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1414889-33-0 C₁₉H₁₆ClF₃N₂O₄ 
• 1414889-35-2 C₂₂H₂₀ClF₃N₂O₃ 
• 1360591-23-6 (S,E)-6-chloro-4-(2-cyclopropylvinyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1414889-37-4 (S,Z)-6-chloro-4-(2-cyclopropylvinyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1414889-36-3 C₁₈H₁₄ClF₃N₂O₃ 
• 1414889-34-1 C₁₈H₁₇ClF₃N₃O₂ 

Relevant academic research and scientific papers

Organocatalytic enantioselective Strecker reaction of cyclic trifluoromethyl-ketoimines

A quinine thiourea promoted enantioselective Strecker reaction of cyclic ketoimines with TMSCN has been developed. The process affords new enantioenriched trifluoromethyl dihydroquinazolinones in high yields and with high enantioselectivities. Copyright

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. This journal is

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. The Royal Society of Chemistry 2012.