14149-38-3Relevant academic research and scientific papers
REGIOSELECTIVE CARBON-CARBON BOND FORMATION AT C2 OF 1,3-THIAZOLE BY REACTION OF N-ETHOXYCARBONYLTHIAZOLIUM CHLORIDE WITH C-NUCLEOPHILES
Dondoni, Alessandro,Dall'Occo, Tiziano,Fantin, Giancarlo,Fogagnolo, Marco,Medici, Alessandro
, p. 3633 - 3636 (1984)
N-Ethoxycarbonylthiazolium chloride generated in situ from 1,3-thiazole and ethyl chloroformate, treated with lithium carbanions of esters, Grignard reagents, silyl enol ethers and esters, undergo nucleophilic addition at C2 affording the corresponding 2-substituted N-ethoxycarbonylthiazolines.
