Tetrahedron Letters p. 3633 - 3636 (1984)
Update date:2022-08-02
Topics:
Dondoni, Alessandro
Dall'Occo, Tiziano
Fantin, Giancarlo
Fogagnolo, Marco
Medici, Alessandro
N-Ethoxycarbonylthiazolium chloride generated in situ from 1,3-thiazole and ethyl chloroformate, treated with lithium carbanions of esters, Grignard reagents, silyl enol ethers and esters, undergo nucleophilic addition at C2 affording the corresponding 2-substituted N-ethoxycarbonylthiazolines.
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