141493-72-3Relevant academic research and scientific papers
Trapping intermediates in an [8 + 2] cycloaddition reaction with the help of DFT calculations
Lage, Marta L.,Fernandez, Israel,Sierra, Miguel A.,Torres, M. Rosario
supporting information; experimental part, p. 2892 - 2895 (2011/08/02)
DFT calculations predict that the [8 + 2] cycloaddition reaction between ketenes and 8-azaheptafulvenes occurs stepwise through antiaromatic zwitterionic intermediates. With adequate modifications of both the electronic properties of the ketene and the re
Cycloadditions of 2,4,6-Cycloheptatriene-1-imines with Chloroketenes: Facile and High-Yield One-Pot Synthesis of 1-Azaazulen-2(1H)-ones
Ito, Kazuaki,Saito, Katsuhiro,Takahashi, Kensuke
, p. 812 - 816 (2007/10/02)
Simple heating of mixtures of N-arylcycloheptatriene-1-imines and acyl chlorides in the presence of an excess amount of triethylamine afforded 1-azaazulen-2(1H)-ones in high yields.The intermediacy of the cycloadducts between the 2,4,6-cycloheptatriene-1-imines and ketenes were confirmed by their isolations.Analogous results were obtained with tropone hydrazones.
